One explanation of the “obesity paradox” in SM patients could be given by Giampetri et al., namely the fact that SM patients have lower expression of 4 genes: CD36 (fatty acid translocase), MARCO (pro-tumor macrophage marker), FABP (Fatty acid-binding protein)4, and FABP7, compared to other cancer patients. This evidence concerns the gene CD36 and systemic mastocytosis.