For example, inhibition of mitochondrialcomplex I (CI, NADH:ubiquinone oxidoreductase) has been linked toneurodegenerative effects like Parkinsonian motor deficits., Additionally, inhibition of mitochondrial complex III (cytochromebc1 complex) was recently proposed as a molecular initiatingevent, potentially triggering neurodevelopmental defects. Furthermore, CI and CIII have also been suspectedto play an important role in cancer, inflammation, and other diseases., Here, NDUFB6 is linked to cancer.