Shared pathways between miR-34a and miR-351 include those related to cancers such as prostate cancer, melanoma, and chronic myeloid leukaemia, as well as pathways involved in cellular metabolism, endocytosis, and key signalling cascades, such as MAPK, phosphoinositide-3-kinase (PI3K-AKT), wingless-type MMTV integration site family (WNT), and adrenergic signalling. The gene discussed is AKT1; the disease is Familial prostate cancer.