ZNF16 and pachyonychia congenita: Pathway analysis using iPathwayGuide identified focal adhesion (FA), cytokine-cytokine receptor interaction (CCRI), extracellular matrix-receptor interaction (ECMRI), human papillomavirus infection (HPVI), and pathways in cancer (PC) as the top five pathways affected by ZNF16 depletion (Fig. 5B and Table 1).