SETD5 expression was analyzed in 100 adipocytic tumors using immunohistochemistry; these 100 tumors consisted of 24 dedifferentiated liposarcomas (DDLPS), 24 atypical lipomatous tumors/well differentiated liposarcomas (WDLPS), 12 myxoid liposarcomas, 5 pleomorphic liposarcomas, and 35 benign adipocytic tumors. The gene discussed is SETD5; the disease is myxoid liposarcoma.