HMOX1 and deep vein thrombosis: Previous studies have indicated that the upregulation of HMOX1 is associated with increased ferroptosis in diabetic human endothelial cells.26 To clarify the functional mechanism of HMOX1 in DVT formation, we first checked the 4D Label Free proteomics data and found that HMOX1 was significantly overexpressed in DVT mice (Figure S9A).