TUGSE: traumatic ulcerative granuloma with stromal eosinophilia; SCC: squamous cell carcinoma; CD30+ LPD: CD30-positive lymphoproliferative disorder; EBV: Epstein–Barr virus; IHC: immunohistochemistry; HRS: Hodgkin/Reed–Sternberg cells; TPPA: Treponema pallidum particle agglutination; FTA-ABS: fluorescent treponemal antibody absorption test; TNF-α: tumor necrosis factor alpha. This evidence concerns the gene TNFRSF8 and lymphoproliferative syndrome.