Wald Wald NJ NJ Cuckle Cuckle H H Brock Brock JH JH Peto Peto R R Polani Polani PE PE Woodford Woodford FP FP Maternal serum-alpha-fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy. The gene discussed is AFP; the disease is spina bifida.