PKM and endothelial dysfunction: The research findings uncover significant PKM2 palmitoylation rates after palmitic acid exposure which agrees with current evidencesupporting PKM2 post-translational modifications as a cause of endothelial injury and cardiovascular dysfunction [14].The endothelial dysfunction triggered by trans fatty acids elaidic and linoelaidic acids was worse than saturated fatty acids becausethese acids lowered NO production more severely and raised inflammatory markers at higher levels.