CCDC88B and Granuloma: Among those, CCDC88B and ANXA11 are potential regulators of apoptosis [29, 34], whereas CCL24 was increased in broncho-alveolar lavage (BAL) of patients with stage 3 sarcoidosis compared to patients with Lo ̈ fgren syndrome [58] and IL23R has been implicated in the formation of granulomas [38].