Tumor locations in IDH-wt astrocytoma were temporal (55; 30.9%), followed by frontal (41; 23.0%), parietal (39 patients; 21.9%), insular (27 patients; 15.2%), thalamic (12 patients; 6.7%) and occipital (4 patients; 2.2%). The gene discussed is IDH2; the disease is neoplasm.