No difference was found in PR (IDH-wt astrocytoma: 18 patients (11.3%); IDH-wt glioblastoma: 24 patients (11.8%), p = 0.99) and biopsy (IDH-wt astrocytoma: 52 patients (32.5%); IDH-wt glioblastoma: 50 patients (25.2%), p = 0.286). The gene discussed is IDH2; the disease is astrocytoma (excluding glioblastoma).