HDL is often referred to as “good cholesterol” because of its heart disease-prevention properties and its role in the elimination of LDL from the bloodstream.[31] Owing to variations in insulin sensitivity and treatment approaches, the increased HDL levels in patients with T1DM may indicate a more advantageous lipid profile in terms of cardiovascular protection.[31] Despite the higher levels of LDL that have been reported, this contrast emphasizes the protective function of HDL in patients with T1DM.[31]. The gene discussed is INS; the disease is type 1 diabetes mellitus.