F2 and deep vein thrombosis: In the same year, another study analyzed the thrombotic occurrence in 146 patients undergoing total knee arthroplasty to explore the risk factors and coping strategies for postoperative lower extremity DVT.[8] The study results showed that advanced age, elevated D-dimer, decreased prothrombin time international normalized ratio (PT-INR), high body mass index, and comorbid internal diseases are risk factors for DVT after TKA.