RPS6KB1 and neoplasm: With median values of 5.146 (tumor) and 4.469 (normal) for GSK3β and 7.057 (tumor) and 6.806 (normal) for S6K1, the expression level of both genes was proved to be significantly lower in tumor tissue compared to normal (p < 0.0001 for both GSK3β and S6K1).