INS and diabetes mellitus: We have also recently reviewed the potential applications of continuous glucose monitoring (CGM) technologies in people at-risk of diabetes, including those with SO [95], highlighting two studies that used CGM to derive algorithms for postprandial impaired glucose tolerance and/or muscle insulin resistance [96,97], a trait of the declining muscle in SO, thereby allowing for early identification of individuals with dysglycaemia before the development of clinical diabetes [95].