Similarly, human studies integrating proteomic and transcriptomic approaches have characterized molecular interactions in sarcopenia and osteoporosis, identifying genes involved in osteoclast differentiation and cytokine–cytokine receptor interaction, including Protein Disulfide Isomerase family A member 5 (PDIA5), Tubulin Beta 1 Class VI (TUBB1), Cytoplasmic FMR1-interacting protein 2 (CYFIP2), Myosin Heavy Chain 7 (MYH7), and Neural cell adhesion molecule 1 (NCAM1) [113]. Here, PDIA5 is linked to osteoporosis.