In contrast, in the overweight/obesity group, age (correlation coefficient: −0.287, 95% CI −0.400 to −0.165, p < 0.001), hypertension (correlation coefficient: 0.201, 95% CI 0.075 to 0.321, p = 0.002), ESR (correlation coefficient: −0.134, 95% CI −0.258 to −0.006, p = 0.040), and ALT (correlation coefficient: 0.314, 95% CI 0.194 to 0.425, p < 0.001) showed significant associations with BMI (Table 2). The gene discussed is ESR1; the disease is obesity due to melanocortin 4 receptor deficiency.