To valorize both the phytochemical richness of M. vulgare and the ancient ethnopharmacological knowledge surrounding it, this study aimed to identify bioactive compounds from 5 organic and 1 aqueous extract and evaluate their potential against a clinically relevant target: Heat Shock Protein 90 (Hsp90), a key molecular chaperone involved in cancer progression and drug resistance [26,27]. The gene discussed is HSP90AA1; the disease is cancer.