It is a correlation activity that was observed in both healthy tissue (positive with CYP2B7P1, ADH1C, AKRB10, and EPHX2 and negative with PTGS1), as well as CC vs. AC (positive with MAOA and negative with EPHX1 and PTGS1) and CRC (positive with ADH1C, ADH5, and AKRB10, and negative with GGT5) (Table 5). This evidence concerns the gene EPHX2 and colorectal carcinoma.