Interestingly, TP53 mRNA from the X126 tumours correlated with genes involved in RNA processing and splicing, transcriptional regulation and chromatin organization, ribosome and RNP biogenesis, nuclear transport, cell cycle and chromosome dynamics, mitotic processes, telomere maintenance and genome stability, DNA replication, recombination and repair, protein complex assembly and modification, and stem-cell-related programmes, while lacking associations with canonical apoptotic, cell cycle regulatory, and differentiation pathways (Figure 5A). Here, TP53 is linked to neoplasm.