PVT1 and autism: Additionally, several of these lncRNAs—Meg3, Pvt1, and Malat1 (with MALAT1 showing reduced expression in the spinal cord)—are involved in GABAergic signalling, which is essential for proper cortical development and implicated in disorders with cortical affection such as age-related cognitive decline, schizophrenia, and autism [37,38,39].