AIPL1 and severe early-childhood-onset retinal dystrophy: Although mutations in AIPL1 are mainly associated with autosomal recessive LCA and early-onset retinal dystrophy (EOSRD), AIPL1 is also linked to less severe IRDs of cone-rod dystrophy [28], juvenile or early-onset RP [28,85], non-early onset RP [86], and late-onset retinal degeneration [87].