AIPL1 and retinal degeneration: Case studies show that mutations associated with retinal degeneration of a wide spectrum of severity occur in the exon 3 [18,28,40,41,85,86,88,91,119,120,121,122,123,124,125,126] and in vitro assays support the indispensability of this region for AIPL1 function [26,61,62,71,116,127].