Hyperglycemia significantly increased the expression of CD36 (p = 0.00023 and p = 0.002), CD69 (p = 0.025 and p = 0.003), CD274 (p = 0.013 and p = 0.008), and TLR-7 (p = 0.36 and p = 0.23) at 24 and 48 h, but there was no significant effect on TLR-7 expression, and TLR-7 expression decreased at 48 h (Figure 5). This evidence concerns the gene CD274 and Hyperglycemia.