Univariate logistic regression analysis showed that higher BMI (Exp (B) = 0.843, 95% CI = 0.760–0.936), elevated Wnt5a (Exp (B) = 0.746, 95% CI = 0.668–0.832) and JAK (Exp (B) = 0.840, 95% CI = 0.773–0.913), lower SFRP5 (Exp (B) = 2.098, 95% CI = 1.637–2.690), and reduced fractional shortening (Exp (B) = 1.110, 95% CI = 1.048–1.175) and ejection fraction (Exp (B) = 1.069, 95% CI = 1.032–1.107) were significant predictors of cardiac disease (p < 0.001). This evidence concerns the gene WNT5A and heart disorder.