A cluster of twenty-one genes: TGM1, SLC6A12, AHNAK2, RCOR2, STRA6, IL27RA, SPINT2, ZSWIM4, RASSF9, SLC7A1, GINS4, PODNL1, CILP2, TMEM119, VCAN, MXRA5, ANPEP, NTN1, MISP3, CD9, NINJ2, exhibited greater than 3.5-fold increase in expression in tumor tissues (Median (Range) = 6.7 (3.5–13.1) fold-increase). The gene discussed is MISP3; the disease is neoplasm.