IL1B and Parkinson disease: Recent findings indicate that IL-1β and IL-6 may be involved in astroglial modulation of adult neurogenesis and dopaminergic vulnerability, as suggested by elevated levels of these molecules in the cerebrospinal fluid of patients with PD [110,114] and as demonstrated by reactive astrocyte expression of IL-6 in the postmortem midbrain and iPSC-derived astrocytes [66,110,115].