The search phrases included “β3 adrenergic receptor” and “beta 3 adrenergic receptor” combined with “agonist”, “antagonist”, “inhibitor”, “heart failure”, “cardiac arrhythmias”, “atherosclerosis”, “myocardial ischemia”, “acute coronary syndrome”, “coronary artery disease”, “angina pectoris”, “myocardial infarction”, “ST-elevation myocardial infarction”, “non-ST elevation myocardial infarction”, “ischemia-reperfusion injury”, “reperfusion injury”, and “hypertension”. The gene discussed is ADRB3; the disease is Hypertension.