PTEN, TP53, ARID1A, KRAS, PIK3CA and PPP2R1A are common mutations overlap between endometriosis and EC [211],Key pathways leading to EC development include Wnt/β-catenin, MAPK/ERK, PI3K/AKT/mTOR, VEGF/VEGFR and p53-p16INK4a [224]. This evidence concerns the gene PIK3CA and endometriosis.