CA-125 is often elevated in endometriosis but also can be in other conditions decreasing its diagnostic value [274],CA 19-9, CEA, SLX and LDH present differing levels in endometriosis and ovarian cancer [276,277],HE4 is more specific comparing to CA-125, however is commonly not elevated in benign lesions [277]. Here, MUC16 is linked to ovarian cancer.