Similarly, reductions in LysoPE levels have been implicated in intestinal inflammation and epithelial injury [20,21], whereas oral LysoPE supplementation has been shown to alleviate peritonitis by decreasing pro-inflammatory mediators (IL-1β, IL-6, and TNF-α) while increasing the anti-inflammatory cytokine IL-10 [22]. This evidence concerns the gene IL6 and peritonitis.