FAAH and Anxiety: Reports link rs324420 to anxiety traits (based on the fronto-amygdaloid mechanisms described above) and—in case studies and functional genetics—to analgesia modulation within the FAAH/FAAH-OUT locus (with FAAH-OUT microdeletion causing extremely low FAAH activity and an analgesia phenotype; this does not directly involve rs324420, but it strengthens the biological plausibility of the FAAH–AEA axis for pain).