CHCHD2 and Parkinson disease: Combining our findings of four known pathogenic variants with two patients with CHCHD2 p.(Phe84LeufsTer6), a positive finding was obtained for 2 (8%) of 25 PD patients with young onset and positive family history, 2 (2.2%) of 91 early-onset PD patients, 5 (2.9%) of 173 patients with positive family history, and 1 (0.9%) of 112 patients with negative family history.