STING1 and systemic sclerosis: Incorporating recent observations on the cyclic GMP–AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, damage-associated molecular patterns (inflammasome activation), and the senescence-associated secretory phenotype would provide a clearer understanding of how the core findings of genomic instability and telomere attrition directly lead to the chronic inflammation and tissue fibrosis seen in SSc.