BDNF and hemorrhage: A recent animal study suggested the role of MED1 neuronal expression in neuroplastic changes, particularly showing that thalamic hemorrhage elicits a significant increase in hippocampal MED1 and Tropomyosin receptor kinase B (TrkB) expression, accompanied by a decrease in Brain-derived neurotrophic factor (BDNF) levels, all of which were restored in rodent models by a combined N-palmitoylethanolamide and luteolin treatment [9].