INPP5E and Retinal dystrophy: In a recently published cohort of Portuguese patients affected by retinal dystrophies of 130 index cases, the INPP5E gene was involved in 1.7% of solved and likely solved cases [4], whereas in a larger Italian cohort of 2970 patients affected by retinal dystrophies, INPP5E was implicated in 0.25% of the solved cohort [5].