Significant reductions were documented following medium- to long-term intake of polyphenol-rich juices: citrus-based formulations fortified with aronia extract lowered CRP alongside homocysteine after six months in patients with MetS [18], while pomegranate juice elicited consistent decreases in CRP both in MetS and type 2 diabetes populations (Table 1) [31,34]. The gene discussed is CRP; the disease is type 2 diabetes mellitus.