Neither in the univariate logistic regression analysis nor after adjustment for the potential confounders—male sex, insomnia treated with medication, hypertension, and smoking status—did any of the four analyzed polymorphisms (CALCRL rs6710852, RAMP1 rs13386048, RAMP1 rs12465864, and RAMP1 rs6431564) reach statistical significance when applying Bonferroni correction for multiple testing (Bonferroni p-value threshold <0.0125). The gene discussed is CALCRL; the disease is insomnia measurement.