Because PRP is rich in biologically active growth factors, such as Transforming Growth Factor-β (TGF-β), Vascular Endothelial Growth Factor (VEGF), Platelet-Derived Growth Factor (PDGF), and Insulin-like Growth Factor (IGF) [10], and has demonstrated regenerative and anti-apoptotic effects in various tissues [11], several recent studies have investigated its potential therapeutic role in PCOS. The gene discussed is VEGFA; the disease is polycystic ovary syndrome.