Moreover, in cancer-associated thrombosis, tumor-derived microparticles bearing high levels of active TF markedly increase the incidence of deep vein thrombosis in mice and are recruited to the thrombus, in part through interactions with neutrophil extracellular traps, providing a mechanistic link between malignancy, NET formation and venous thrombosis. The gene discussed is TF; the disease is Venous thrombosis.