Univariate Cox regression analysis indicated that age, COPD, concurrent bacterial or fungal infections, IL-6, D-dimer, CRP, and high-value groups for opacity score, volume of opacities, percentage of opacities, volume of high-attenuation opacities and mean HU of the total lung were significantly associated with adverse outcomes (p < 0.05). The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.