The current WHO classification recognizes several molecularly defined entities: supratentorial ZFTA fusion-positive (ST-ZFTA), supratentorial YAP1 fusion-positive (ST-YAP), posterior fossa type A (PFA), posterior fossa type B (PFB), and rare subtypes such as spinal MYCN-amplified ependymoma [3]. This evidence concerns the gene YAP1 and ependymoma.