CAMSAP2 and neoplasm: For example, CAMSAP2 is involved in tumor cell invasion and metastasis by stabilizing the minus-end of non-centrosomal microtubules; abnormal activation of γ-TuRC, a core factor in microtubule nucleation, may promote the over-assembly of centrosomal microtubules, thereby enhancing the malignant phenotype of tumor cells; and ASPM may be involved in tumor progression by regulating spindle microtubule dynamics.