CAMSAP3 and lung carcinoma: Unlike other members of the family, CAMSAP3 has tumor suppressor potential: it inhibits cell migration through an EMT-dependent mechanism [59]; and it acts through multiple mechanisms in lung cancer, inhibiting both tumor invasion and angiogenesis by negatively regulating HIF-1α mRNA stability [60]; and inducing a cellular senescence-like phenotype by mediating cell cycle arrest through ERK phosphorylation regulation [27].