For example, CAMSAP1 promotes tumor progression in hepatocellular carcinoma, but its mutation correlates with elevated chemosensitivity in small cell lung cancer; CAMSAP2 significantly promotes invasive metastasis in a variety of solid tumors such as hepatocellular carcinoma and colorectal carcinoma; and CAMSAP3 can negatively regulate cell migration through an EMT-dependent mechanism. The gene discussed is CAMSAP3; the disease is small cell lung carcinoma.