Interest in the field of epigenetics, fetal programming, and the developmental origins of health and disease hypothesis [17] have led to numerous studies to define how gestational obesity affects metabolic programming (including insulin resistance) as well as circulating levels of hormones (insulin, cortisol, and leptin) and glucose in the offspring of sheep [18,19,20,21] and humans [14,15,22,23,24,25,26]. Here, LEP is linked to Insulin resistance.