In a separate investigation, researchers also found that resveratrol reduced the growth of melanoma cells in vitro and significantly slowed lung metastasis in mice injected with melanoma cells by increasing immune-stimulating factors like CXCL10 and IFN-γ, reducing tumor angiogenesis, and limiting infiltration of immunosuppressive regulatory T cells [Tregs] in the lung [87]. This evidence concerns the gene CXCL10 and melanoma.