CD4 and asthma: Several adaptive immune populations, including B cells (FDR = 0.020), CD4 T cells (FDR = 0.020), DC1 (FDR = 0.020), DC2 (FDR = 0.020), migratory DCs (FDR = 0.020), and proliferating T cells (FDR = 0.020), were specifically associated with asthma (Figure 1), supporting the contribution of adaptive immunity to disease pathogenesis [35,36,37,38].