It also regulates glucose transporters (GLUT1 and GLUT3) and glycolytic enzymes (hexokinase 1 [HK1], HK2, and lactate dehydrogenase A [LDHA]), enabling tumour cells to maintain energy production under low oxygen conditions through the Warburg effect, characterised by high rates of aerobic glycolysis and lactate production. This evidence concerns the gene HK1 and neoplasm.