miR-210 is directly upregulated by HIF-1α during hypoxia and promotes cancer stem cell phenotypes, epithelial–mesenchymal transition, and immune suppression by regulating CD24, CD44, CD133, E-cadherin, vimentin, and Snail expression, while simultaneously modulating HIF-1α through negative feedback loops that maintain cellular adaptation to hypoxic stress [71,72]. Here, HIF1A is linked to cancer.