The most common and shared pathways were “systemic lupus erythematosus”, “signaling by Wnt”, “Notch signaling”, “signaling by nuclear receptors”, “reactome_signaling_by_rho_gtpases_miro_gtpases_and_rhobtb3”, “olfactory signaling pathway”, “ESR mediated signaling”, etc. See Supplementary Material File S2: Tables S59–S64 for all overrepresented pathways. This evidence concerns the gene ESR1 and systemic lupus erythematosus.