Successful engraftment was observed in all patients: in SCD, a rapid and sustained normalization of Hb 4 months after infusion was observed, associated with a marked increase in HbF synthesis, associated with resolution of vaso-occlusive events and normalization of the markers of hemolysis; in the two β-thalassemic patients, rapid improvements of hematological parameters were observed, associated with development of transfusion-independence [107]. This evidence concerns the gene GSTM1 and Schnyder corneal dystrophy.