Supporting these findings, both random forest and SHAP analyses further confirmed the dominant diagnostic contribution of DGCR8 and DICER1 in AML, while in MDS, DGCR8 remained the leading contributor, followed by TARBP2 and DICER1 at moderate levels (Supplementary Figures S1–S3). This evidence concerns the gene TARBP2 and myelodysplastic syndrome.