These controversies will be discussed in more detail in the next paragraph, but they include the role of specific NET imaging studies in NET/pNET diagnosis in/ZES-MEN1/MEN1 patients; which tumor localization studies should be performed both initially and during follow-up studies; and when the tumor localization studies should be performed during follow-up and with what frequency [57,58,201,291,462,463,470,471,472,473]. The gene discussed is MEN1; the disease is neoplasm.