For the cohort with light pressure sensation testing (Supplemental Table S1) the highest quartile of Cer-16 had the lowest prevalence of self-reported very good or excellent health; the highest prevalence of hypertension; the least number of blocks walked in the prior week; the highest amount of prevalent and incident diabetes; the highest total and LDL-cholesterol and CRP and IL-6 levels; and the lowest eGFR levels. The gene discussed is CRP; the disease is hypertensive disorder.